BDBM111816 (2E,5E)‐2,5‐bis[(2,3‐ dimethoxyphenyl)methylidene]cyclopentan‐1‐one (15)

SMILES COc1cccc(\C=C2/CC\C(=C/c3cccc(OC)c3OC)C2=O)c1OC

InChI Key InChIKey=VNKCZJKGJAEOCW-WXUKJITCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 111816   

TargetProstaglandin E synthase(Homo sapiens (Human))
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia

LigandPNGBDBM111816((2E,5E)‐2,5‐bis[(2,3‐ dimethoxyp...)
Affinity DataIC50:  1.04E+4nMpH: 7.0 T: 2°CAssay Description:The assay buffer contained 100 mM KHPO4 (pH 7.0), 2 mM EDTA and 2.5 mM reduced GSH. 100 µL of reaction buffer containing human recombinant mPGES...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed